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    Cardiovascular Genetics and Genomics for the Cardiologist Illustrated Edition

    by Victor J Dzau M.D. (Editor), Choong-Chin Liew (Editor)

    Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way cardiovascular medicine is practiced • what material has immediate relevance to the practicing clinician • how to incorporate genetics and genomics in your practice to ensure up-to-date patient care

    The book opens with introductory chapters, then discusses: • cardiovascular single gene disorders • cardiovascular polygenic disorders • therapies and applications

    Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.

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    Cardiovascular Genetics and Genomics Illustrated Edition

    by Dan M. Roden (Author)

    This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.

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    Cardiovascular Gap Junctions (Advances in Cardiology) 1st Edition

    by S. Dhein (Editor)

    In recent years, gap junction research in the cardiovascular system has considerably improved the understanding of cardiac function and the vasculature in health and disease. The present book focuses on the communication of intercellular gap junctions in the cardiovascular system but also includes aspects of physiology, medicine and cell biology. The first part of this volume highlights the principal aspects of these intercellular channels, allowing the readers unfamiliar with the field to get a deeper understanding of the physiology, pharmacology and regulation of gap junctions. The second part elucidates their role in the pathophysiology of important cardiovascular diseases, e.g. arrhythmia, heart failure, ischemia, atrial fibrillation, diabetes and arteriosclerosis. This book is of special interest to cardiologists, physiologists, pharmacologists, cardiovascular scientists, biophysicists, cell biologists as well as to industrial companies engaged in cardiovascular medicine and research.

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    Cardiovascular Engineering: Technological Advancements, Reviews, and Applications

    by Dyah Ekashanti Octorina Dewi (Editor), Yuan Wen Hau (Editor), Ahmad Zahran Mohd Khudzari (Editor), Ida Idayu Muhamad (Editor), Eko Supriyanto (Editor)

    This book highlights recent technological advances, reviews and applications in the field of cardiovascular engineering, including medical imaging, signal processing and informatics, biomechanics, as well as biomaterials. It discusses the use of biomaterials and 3D printing for tissue-engineered heart valves, and also presents a unique combination of engineering and clinical approaches to solve cardiovascular problems. This book is a valuable resource for students, lecturers and researchers in the field of biomedical engineering.

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     Cardiovascular Engineering: A Protective Approach 1st Edition

    by Shu Q. Liu (Author)

    Cardiovascular engineering principles and practices with a focus on disease prevention

    Aimed at advanced students taking cardiovascular, regenerative, and tissue engineering courses, Cardiovascular Engineering: A Protective Approach explores applications of protective engineering strategies and technologies to common cardiovascular disorders. A protective approach to cardiovascular engineering involves studying the naturally occurring mechanisms that protect molecules, cells, and organs from injury and dysfunction. The goal is to use this understanding to design and develop engineering-based therapeutic strategies and technologies that prevent cardiovascular injury and disease. Readers will learn the fundamental and applied aspects of cardiovascular engineering.

    Coverage includes:

    • Foundations of cardiovascular protective engineering • Development of the heart, blood vessels, and blood cells • Stem cells and regeneration • Structure and function of the heart and blood vessels • Cytokines and growth factors in cardiovascular disease • Mechanisms of disease • Systems protective mechanisms against injury • Protective engineering strategies • Systemic hypertension • Atherosclerosis and arterial aneurysms • Ischemic heart disease and ischemic stroke • Cardiomyopathies and congenital heart disease

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    Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles Illustrated Edition

    by Flemming R. Cassee (Editor), Nicholas L. Mills (Editor), David Newby (Editor)

    This book assists scientists, toxicologists, clinicians, and public health regulators to understand the complex issues that determine the impact of air pollution on the cardiovascular system. It covers a range of relevant topics including particulate matter (PM) sources and characterization, methods of exposure, impact of PM on cells and systems, role of particles in the pathophysiology of cardiovascular disease, risk assessment, and potential environmental and therapeutic interventions.

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    Cardiovascular Diseases: Nutritional and Therapeutic Interventions 1st Edition

    by Nilanjana Maulik (Editor)

    With cardiovascular disease remaining one of the primary causes of morbidity and mortality worldwide, there is a great need to further understand the molecular basis of this disease class and develop new therapeutic or preventative measures. Cardiovascular Diseases: Nutritional and Therapeutic Interventions presents up-to-date information on the pathobiology of cardiovascular diseases, emphasizing emerging therapeutics and nutritional interventions. The book is divided into four parts: epidemiology, epigenetics, pathobiology, and therapies for cardiovascular diseases.

    Part I details epidemiological studies, highlighting the extent of the clinical problem. Part II describes the genetic and, primarily, epigenetic modifications associated with cardiovascular disease, including the importance of DNA methylation status and the possibility of early intervention using simple dietary modifications. The text also discusses histone modifications associated with disease and potential therapeutic synthetic and dietary compounds such as resveratrol and garlic. Covering the etiology and pathobiology, part III discusses lipid regulation, micro-RNAs, emerging cell-based therapies, and new receptor targets for therapeutics as well as targeted imaging. It also describes the link between cancer therapies and cardiomyopathy and the potential of vitamin C to ameliorate this effect.

    Part IV focuses on therapeutic and nutritional interventions, namely, stem cell therapies, emerging nanomedicines, and a wide range of dietary interventions. These include general healthy diets, fruits and vegetables, botanicals, effects of specific compounds such as antioxidants, and discussions on garlic, curcumin, and resveratrol. The text also covers lifestyle factors, emphasizing the importance of stress in the occurrence of and meditation and yoga in the management of cardiovascular disease. This book provides a comprehensive reference for clinicians and scientists, combining epidemiology, prevention, and modern treatment strategies.

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    Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and their Interaction

    by Nikolaos Papageorgiou (Author)

    Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared, provide a sound understanding of the interplay between inherited and acquired risk factors. The book provides a much needed reference for this rapidly growing field of study. By combining the latest research within the structured chapters of this reference, a better understanding of genetic and environmental contribution to cardiovascular disease is found, helping to substantiate further investigations in the field and design prevention and treatment strategies.

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    Cardiovascular Diseases: From Molecular Pharmacology to Evidence-Based Therapeutics 1st Edition

    by Y. Robert Li (Author)

    Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases.

    • Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and treat cardiovascular diseases • Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology • Includes guidelines and algorithms for pharmacotherapeutic management of cardiovascular diseases • Uses case presentations and study questions to enhance understanding of the material • Serves as a resource for pharmaceutical and medical students and researchers interested in cardiovascular issues

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    Cardiovascular Diseases and Depression: Treatment and Prevention in Psychocardiology

    by Bernhard T. Baune (Editor), Phillip J. Tully (Editor)

    The world is witnessing a burgeoning global epidemic of chronic cerebro- and cardiovascular disease and depression disorders. The reader will find this comprehensive book to be a long-needed, up-to-date knowledge base on these increasingly recognized comorbid conditions that have long-term consequences for individual function and well-being and society in general. This comprehensive book outlines the complex and bidirectional relationship between various types of depression and cerebro- and cardiovascular diseases. It is written by a range of experts in the field, including psychiatrists, cardiologists, neuroscientists, psychologists, and epidemiologists, with the aim of presenting and discussing the most recent evidence on the pathophysiology, neurobiology, and clinical presentation of these common and disabling comorbid conditions and the available pharmacological, psychological, and behavioral interventions. By elucidating the underlying clinical and neurobiological mechanisms in the brain and the rich interplay between the body and the brain biology, the book brings together the latest knowledge of this overlapping area in Psychiatry and Cardiology. The clear descriptions of evidence-based approaches to clinical treatment ensure that it will serve as both an up-to-date overview and a future guide for practicing clinicians and graduate students.

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    Cardiovascular Disease in the Elderly, Fourth Edition

    Edited By Wilbert S. Brono?, Jerome L Fleg, Michael W. Rich

    Individuals 65 years of age or older currently account for over eighty percent of all cardiovascular disease-related deaths. With advances and breakthroughs in modern medicine that are allowing people to live longer, the number of older adults in this country will continue to grow exponentially over the next several decades. Cardiologists, geriatricians, and other clinicians caring for the elderly will require??”at the very least??”a basic understanding of cardiovascular disorders that commonly affect the older patient. In the Fourth Edition of this classic text, each chapter has been thoroughly updated to provide a comprehensive, yet readable overview of the epidemiology, pathophysiology, evaluation, and treatment of cardiovascular disorders in older adults.

    Cardiovascular Disease in the Elderly :

    provides an in-depth discussion of the elderly patient in the clinical setting considers the impact of multiple coexisting conditions, frailty, polypharmacy, and patient preferences in optimizing disease management each chapter written by recognized experts in the evaluation and management of older individuals with cardiovascular disease

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    Cardiovascular Disease in Racial and Ethnic Minorities

    by Keith C. Ferdinand (Editor), Annemarie Armani (Editor)

    Cardiovascular heart disease mortality in African Americans is the highest of all major racial/ethnic subpopulations in the United States. Examining race and ethnicity, Cardiovascular Disease in Racial and Ethnic Minorities will reveal that there are unacceptable healthcare disparities in risk factor prevalence, disease states, and cardiovascular outcomes in the United States. Written by a team of experts, Cardiovascular Disease in Racial and Ethnic Minorities examines to what degree biomedical and scientific literature can clarify the impact of genetic variation versus environment as related to cardiovascular disease. Chapters illustrate the magnitude of cardiovascular and metabolic disparities and the effect of environment on diseases.

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    Cardiovascular Disease in AIDS 2nd Edition

    by Giuseppe Barbaro (Editor), Franck Boccara (Editor), Paul Skolnik (Foreword), Giorgio Barbarini (Contributor)

    This book focuses on some of the new clinical and biological insights related to HIV-associated metabolic and cardiovascular complications in the HAART era. The introduction of highly active antiretroviral therapy (HAART) has altered cardiovascular manifestations in HIV. On the one hand, HAART has significantly improved the quality of life of HIV-infected patients. On the other hand, the early data have raised some concerns, creating an intriguing clinical scenery.

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    Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors 2nd Edition

    by Bnf (British Nutrition Foundation) (Editor), Sara Stanner (Editor), Sarah Coe (Editor), Keith N Frayn (Contributor)

    A comprehensive, accessible summary of the latest research in heart disease risk factors

    Cardiovascular Disease (CVD) is a major cause of early death and disability across the world. The major markers of risk—including high blood cholesterol, smoking, and obesity—are well known, but studies show that such markers do not account for all cardiovascular risk. Written by a team of renowned experts in the field, this comprehensive and accessible book examines the evidence for emerging and novel risk factors, and their relationship with diet and nutrition.

    Fully updated throughout, Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors, 2nd Edition covers everything from the epidemiology of cardiovascular disease, to genetic factors, to inflammation and much more – offering invaluable advice on reducing risk factors and preventing CVD. This new edition:

    Authoritatively reports on the link between emerging aspects of diet, lifestyle and cardiovascular disease risk Focuses on novel risk factors of CVD, including the human gut microbiome and fetal and childhood origins, and how it can be prevented Features recommendations for interventions and future research Includes references, commonly asked questions that summarise the take-home messages, and an online glossary Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors, 2nd Edition is an important book for researchers and postgraduate students in nutrition, dietetics, food science, and medicine, as well as for cardiologists and cardiovascular specialists.

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    Cardiovascular Disease and Health in the Older Patient Expanded from Pathys Principles and Practice of Geriatric Medicine 5th Ed

    by David J. Stott (Editor), Gordon D. O. Lowe (Editor)

    As improvements in living conditions and advances in modern medicine lead to increased life expectancy and the number of older adults world-wide continues to grow, so the number of older individuals with cardiac and cerebrovascular disease is rising. Over eighty per cent of all cardiovascular disease-related deaths now occur in patients aged sixty five or older. The high prevalence of co-morbidities, frailty and cognitive decline amongst older patients requires that a holistic approach to the management of cardiovascular disease is required.

    Written and edited by leading experts in the field, ‘Cardiovascular diseases and health in the older patient’ provides scholarly evidence and data which explain why treating an older patient with cardiovascular disease is often different from treating a young or middle-aged patient with the same disease. The chapters have been updated and expanded from the cardiovascular section of the renowned ‘Pathy’s Principles and Practice of Geriatric Medicine’, edited by Alan J. Sinclair, John E. Morley and Bruno Vellas. The revised chapters contain updated evidence and references to recent clinical practice guidelines in Europe and North America, this book provides complete, authoritative information on this major cause of death, poor health and disability in old age.

    Covering the epidemiology, pathophysiology and management of cardiovascular disease in the older patient, the book is an excellent reference at all clinical and pre-clinical levels and will appeal particularly to geriatricians, cardiologists, and GPs, as well as cardiac specialist nurses and practice nurses.

    With a Foreword by Stuart M. Cobbe.

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    Cardiovascular Diabetology Clinical Metabolic and Inflammatory Facets

    by E.Z. Fisman (Editor), A. Tenenbaum (Editor)

    The prevalence of obesity, metabolic syndrome and diabetes - three links of the same ‘atherothrombotic chain’ - has reached pandemic proportions worldwide. As a result, our civilization is at war against a threatening enemy: cardio-diabetes. Several independent physiological processes underlie the clustering of cardio-diabetes, including central obesity, insulin resistance, dyslipidemia, inflammation, impaired glucose tolerance, and hypertension. Early detection is of overwhelming importance for public health. The complex and intimate relationship between cardiovascular disease and diabetes from basic science to clinical and therapeutic concerns is discussed in this outstanding book. Beginning with molecular, biochemical, inflammatory and cellular aspects, this publication continues with histological and pathophysiological issues, details particular problems in specific metabolic and clinical settings, and finally analyzes several aspects of clinical pharmacology focusing on the optimal management of combined dyslipidemia and non-insulin antidiabetic therapy in cardiac diabetic patients. This book will be a gain in knowledge for every cardiologist, diabetologist, specialist in internal medicine, nutritionalist, general physician and medical student.

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    Cardiovascular Development Methods and Protocols 2nd Edition

    by Xu Peng (Editor), Warren E. Zimmer (Editor)

    This second edition brings together a variety of method used in the field of cardiovascular development research. Chapters guide readers through protocols on lymphatic development, lymphatic staining techniques, lymphatic endothelial, tissue clearing techniques, and muscle cell isolation and culture. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls

    Authoritative and practical, Cardiovascular Development: Methods and Protocols, Second Edition seeks to aid scientists in understanding new state-of-the-art techniques in the field of cardiovascular development research.

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    Cardiovascular Computing Methodologies and Clinical Applications 1st ed

    by Spyretta Golemati (Editor), Konstantina S. Nikita (Editor)

    This book provides a comprehensive guide to the state-of-the-art in cardiovascular computing and highlights novel directions and challenges in this constantly evolving multidisciplinary field. The topics covered span a wide range of methods and clinical applications of cardiovascular computing, including advanced technologies for the acquisition and analysis of signals and images, cardiovascular informatics, and mathematical and computational modeling.

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    Cardiovascular Complications of Respiratory Disorders

    Author(s): Miguel Ángel Martínez-García, Jean-Louis Pépin and Mario Cazzola

    This Monograph provides an update on cardiovascular disease complications and treatment implications for respiratory diseases, based on current scientific evidence and considered from an epidemiological, pathophysiological and clinical point of view. This book also discusses the future challenges when studying the complex relationship between these two groups of disorders.

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    Cardiovascular Complications of COVID 19 Risk Pathogenesis and Outcomes

    by Umair Mallick (Author)

    This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels of cardiovascular and metabolic complications. A myriad of pathogenetic mechanisms has come to the surface. There is still much research required to define whether cardiovascular disease causes COVID-19 complications or that cardiovascular disease appears as a result of the infection and which mechanisms are responsible. With cardiovascular and metabolic diseases already at pandemic levels and expected to increase further, this book provides readers with an urgent and thorough analysis of this association.

    Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes provides answers to the increasing numbers of questions related to heart disease in COVID-19, highlighting the association between these pandemics and including risk factors, mechanisms and how these may impact diverse patients populations. It describes how COVID-19 impacts older patients and those with metabolic illnesses such as obesity and diabetes mellitus, while providing an overview of the observed gender dichotomy among patients. It therefore represents an essential resource not only for all cardiovascular physicians but also for any healthcare professionals managing patients with these diseases or those exploring COVID-19.

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