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Endoscopic Biopsy Interpretation: A Practical Guide
by M. Priyanthi Kumarasinghe (Editor), Ian Brown (Editor)
The volume of endoscopic biopsies being performed continues to grow rapidly and they now represent one of the most common specimens encountered in routine surgical pathology practice. It is essential to maintain the balance between the speed and accuracy while integrating emerging sophisticated pathology techniques into endoscopic biopsies in routine practice. Microscopic appearance is virtually diagnostic of certain diseases. In others a diagnosis may be rendered only after correlating the microscopic pattern with clinical clues aided by ancillary tests. This text provides a guide to systematic approach of endoscopic biopsies to render a safe, quick and accurate pathological diagnosis in an integrated manner as well as important information that pathologists and clinicians should know to get the best value of endoscopic biopsies. The first chapter introduces the key microscopic features that are normal and abnormal in the gut mucosa as appreciated in an endoscopic biopsy. The second chapter presents a general overview highlighting the neoplastic and non- neoplastic patterns that are common to the entire tubular gut. Because some patterns are common to many sites, an overarching chapter gives the reader a generalized approach, which will be further refined in subsequent site specific chapters. The disease etiologies of each pattern are discussed, with emphasis placed on the most common causes that will be encountered in clinical practice. The subsequent chapters that follow then concentrate on patterns encountered at specific anatomical locations. Under each anatomical location (esophagus, stomach, small intestine and large intestine) site specific patterns of both neoplastic and non-neoplastic conditions are described. Conditions that affect many sites in the gastrointestinal tract are discussed in detail in the most relevant site chapter, but are referred to in other chapters as the reaction pattern/s they produce at that site is discussed. Ancillary tests that are required for a diagnosis of some diseases in particular neoplastic conditions are listed with tips for interpretation. This is presented mostly in a table format to assist day-to-day quick reference. In keeping with recent advances of using small biopsies for testing clinically relevant bio markers, important information that the pathologists and clinicians need to know is highlighted in appropriate sites. Authored by experts in the field, each chapter is presented under headings that include diagnostic features, patterns with relevant endoscopic and clinical clues, traps and overlapping features, and appropriate ancillary tests including clinically relevant molecular signatures in endoscopic biopsies.
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Frozen Section Library: Appendix, Colon, and Anus (Frozen Section Library, 4) 2010th Edition
by Nicole C. Panarelli (Author), Rhonda K. Yantiss (Author), Philip T. Cagle (Series Editor)
As a handbook for practicing pathologists, this book will be an indispensable aid to diagnosis and avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts will be readily accessible to the users of this handbook. Currently, there is no other up-to-date single-source reference specifically focused on frozen sections of the lower gastrointestinal tract.
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Frozen Section Library: Liver, Extrahepatic Biliary Tree and Gallbladder
by Rhonda K. Yantiss (Editor)
The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Liver, Extrahepatic Biliary Tree and Gallbladder provides a convenient reference for use during intraoperative consultation. The volume addresses commonly encountered challenges, such as the diagnosis of primary and secondary hepatic neoplasms and assessment of gross abnormalities of the gallbladder. The assessment of frozen section biopsies for liver transplantation, a challenging and increasingly encountered situation, is detailed in the form of histologic criteria that should be reported. Emphasis is placed on the differential diagnoses of gross and microscopic findings with attention to potential pitfalls and artifacts encountered on frozen section. gross and microscopic images are provided as well as user-friendly tables for quick reference.
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Frozen Section Library: Lymph Nodes
by Cherie H. Dunphy (Editor)
The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Lymph Nodes highlights the usefulness of techniques such as touch preparation cytology and fine needle aspiration (FNA) cytology, as well as FNA biopsy. This fascicle also suggests proper handling for subsequent ancillary studies, including flow cytometric, cytogenetic, and molecular studies. Special emphasis is given to the limitations of frozen section diagnosis in lymph node pathology. All chapters are written by experts in their fields and include the most up to date scientific information. This book serves as a very useful resource for physicians in the frozen section room and in intra-operative consultation situations dealing with, and interested in, this very complex field of diagnostic pathology. Frozen Section Library: Lymph Nodes is of great value to pathologists, residents, and fellows who diagnose pathologic processes involving lymph nodes. Cherie H. Dunphy, M.D. is Professor of Pathology and Laboratory Medicine, Executive Director of Hematopathology and Hematopathology Fellowship Department of Pathology and Laboratory Medicine University of North Carolina Chapel Hill, NC.
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Frozen Section Library: Bone 2011 Edition
by Hameed, Omar, Wei, Shi, Siegal, Gene P.
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Frozen Section Library: Endocrine Organs (Frozen Section Library, 12) 2014th Edition
by Qihui "Jim" Zhai (Editor)
The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario.
Written by expert surgical pathologists, Frozen Section Library: Endocrine Organs presents common and practical problems including follicular adenoma versus follicular carcinoma, papillary thyroid carcinoma versus reactive change and freezing artifact, follicular variant of papillary thyroid carcinoma, and medullary thyroid carcinoma. Anaplastic carcinoma, thyroid lymphoma, resection margin of a pancreatic endocrine tumor, pheochromocytoma within an adrenal gland and extra- adrenal gland, parathyroid tissue versus a thyroid tissue and versus a lymph node are also explored in detail. All chapters are illustrated with color pictures and accompanied legends.
As a handbook for practicing pathologists, this volume is an indispensable aid to diagnosis and for avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts are readily accessible. Tables and charts provide guidance for differential diagnosis of various histological patterns. Frozen Section Library: Endocrine Organs is a highly valuable guide for practicing surgical pathologists, both community and academic, and to pathology residents and fellows.
Qihui "Jim" Zhai, MD, FCAP, is Professor of Laboratory Medicine and Pathology, Mayo Clinic Florida, Jacksonville, FL.
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Atlas of Surgical Pathology Grossing (Atlas of Anatomic Pathology) 1st ed
by Monica B. Lemos (Editor), Ekene Okoye (Editor)
This book is a unique surgical pathology grossing atlas, comprised of a collection of photos of various anatomic specimens frequently encountered in routine and frozen surgical pathology practice, including various organ systems. The photos in this atlas have been collected over many years of practicing surgical pathology in one of the largest medical centers in the world, and include emphasis on important anatomic landmarks and explanations on how to properly orient, section and sample anatomic specimens. The use of actual gross images allows readers to more readily apply the grossing tips to actual specimens that they encounter at the grossing bench. Each chapter is arranged by organ system and includes essential tips for grossing each specimen and sample dictations with all the essential elements that must be addressed for proper assessment of each organ specimen.
Written by expert pathologists, Atlas of Surgical Pathology Grossing is an excellent resource for pathologists, medical and pathology assistant students, residents, both in surgery and pathology, and pathology assistants.
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