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    Cardiac CT, PET and MR 3rd Edition

    850 1,750 

    Cardiac CT, PET and MR 3rd Edition

    de Vasken Dilsizian (Editor), Gerald M. Pohost (Editor)

    complete guide to non-invasive imaging techniques in cardiology

    Today?s imaging technologies offer cardiologists more ways than ever to diagnose conditions of the heart without the need of endoscopies and other invasive procedures. Now in its third edition,Cardiac CT, PET and MRI continues to provide an in-depth explanation of these tools and their correct applications, while also exploring cardiac imaging?s most recent and groundbreaking developments.

    This wide-ranging guide places CT, PET and MRI in a practical context, illustrating clearly their respective functions as they apply to specific cardiological disorders and clinical situations. With the addition of seven new chapters, it also offers an expanded insight into PET ? an increasingly popular and affordable diagnostic utility, hitherto underexplored in texts devoted to imaging. Cardiac CT, PET and MRI includes:

    Clinically focused examinations of CT, PET and MRI ? the three most popular non-invasive imaging modalities Illustrative full-color photos and images Access to a companion website featuring additional content Cardiologists, radiologists, nuclear medicine physicians, physicists, and imaging technologists alike will find the third edition of Cardiac CT, PET and MRI an informative and accessible resource with a direct use in their day-to-day practice.

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    Cardiac CT: Diagnostic Guide and Cases 1st ed

    de Zheng-yu Jin (Editor), Bin Lu (Editor), Yining Wang (Editor)

    Over the past few decades there have been major advances in computed tomography (CT) to improve the performance of cardiac imaging. Thanks to the improved scanning speed, power boost tubes, and increased-width detectors, the latest CT technology delivers greater coverage, better spatial and temporal resolution, and functional information on cardiac diseases. Focusing on cardiac CT imaging, this book offers case-based information on cardiac diseases, presents the current technical status, and highlights applications, helping readers systematically understand how cardiac CTs are performed and interpreted in clinical practice. Divided into six chapters, it broadly discusses the characteristics of CT imaging and its applications to coronary artery disease (CAD); non-atherosclerotic coronary artery disease; congenital heart disease; cardiac neoplasms; cardiomyopathy and aortic diseases.

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    Cardiac Defibrillation

    350 700 

    Cardiac Defibrillation

    Author(s):Damir Erkapic, Tamas Bauernfeind

    Sudden cardiac death and ventricular arrhythmia play a prominent role in mortality in our era. One of the biggest milestones in the therapy of ventricular arrhythmias was the invention of cardiac defibrillation. There were several important developments in the last decades, making nowadays automated external and internal defibrillators widely available. However, the rapid evolution and high differentiation of available options presents a challenge to be kept "up-to-date". With this book, we would like to review the actual guidelines and give practical advices concerning of indications in cardiomyopathy patients, possible contraindications and complications, the perioperative management including anticoagulation and antibiotics, and the programming and follow-up of defibrillator devices.

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    Cardiac Development

    550 1,100 

    Cardiac Development

    by Margaret Loewy Kirby (Author)

    Offering an understanding of heart tube formation from the cardiogenic fields, this illustrated book covers topics such as myocardial function, cardiac innervation, conduction system development, evolutionary developmental biology of the heart, and myocardial stem cells.

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    Cardiac Diagnosis for Acute Care: The Np's and Pa's Guide to a Comprehensive History and Deciphering the Differential 1st Edition

    by Leslie E. Janik MSN ARNP ACNP-BC (Author)

    Helps clinicians to systematically look beyond the obvious to arrive at a correct diagnosis

    Written specifically for both novice and experienced cardiovascular clinicians in acute care settings, this is the only resource to focus on the art of conducting an in-depth patient history. Too often, patients will tell their first provider one thing and their second provider another. Even when asked the exact same question, patients' stories can inexplicably change. Clinicians can save time, effort, and cost by parsing out conflicting patient histories with a specific and detailed line of questioning. If recorded accurately and interpreted correctly, a comprehensive history alone may obtain a correct diagnosis without exhaustive and expensive evaluations.

    This book includes two clinical scenarios for chief complaints that cardiovascular clinicians may see in their practice. Unpacking these scenarios challenges clinicians to look beyond the obvious and recognize atypical presentations. Each scenario dissects then discusses the history and other pertinent patient information to illuminate subtle differences in the process of information gathering. With this breakdown, the clinician can then identify if the patient has an acute cardiovascular issue. Each chapter ends with a sample of “how to present the patient” to an MD or peer and describes common pitfalls and assumptions to avoid.

    Key Features:

    Focuses specifically on acute cardiovascular issues in acute care settings Referenced by chief complaint or consultation questions Targets patient history portion of the workup Exams subtle differences between cardiac diagnosis versus noncardiac diagnosis based on how patient history is taken Highlights common errors in review of information using electronic medical records versus standard questioning

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    Cardiac Drug Therapy 8th Ed

    1,450 2,900 

    Cardiac Drug Therapy 8th Ed

    de M. Gabriel Khan (Author)

    This book is an essential guide to the medical treatment of the cardiac patient and presents core principles of cardiovascular therapeutics as well as drug recommendations. Major classes of drugs are featured, including beta-blockers, ACE inhibitors, calcium antagonists, diuretics, and antiplatelet agents and unique insights into the controversies surrounding the use of specific drugs are explored, with answers given to the question: do beta blockers and diuretics really cause diabetes? Properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs are examined. This revised edition is thoroughly updated and addresses the entire spectrum of heart disorders, such as hypertension, angina, myocardial infarction, heart failure, arrhythmias, cardiac arrest, and dyslipidemias. New chapters include endocrine heart diseases, management of cardiomyopathies, and newer agents. In addition, topics such as cardiac drugs in pregnancy and lactation and drug interactions are covered. Cardiac Drug Therapy, Eighth Edition, is an authoritative and clinically relevant resource for cardiologists, cardiology fellows, and internists.

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    Cardiac Drugs 2nd Edition

    1,000 2,000 

    Cardiac Drugs 2nd Edition

    by Kanu Chatterjee (Editor), MD Topol, Eric J. (Editor)

    Cardiac Drugs is the latest edition of this comprehensive resource, completely revised to provide up-to-date information on the rapidly evolving field of cardiovascular drugs. The book is divided into thirteen chapters, focusing on cardiovascular comorbid conditions, with extensive coverage of cardiovascular disease management in patients with co-existing diabetes, dysmetabolic syndrome and pregnancy. The first two chapters cover vasodilators and neurohormone modulators, and positive inotropic drugs, and subsequent chapters cover drugs for specific conditions including dyslipidemia, dysrhythmia, stable angina, and pulmonary hypertension. The final chapter `Future Direction - Pharmacogenomics' provides insight into the exploration of the human genome for opportunities to improve therapeutic precision in cardiovascular medicine. This new edition of Cardiac Drugs also incorporates the latest JNC 8 (Joint National Committee) guidelines on hypertension, highlighting their key differences to previous guidelines. Enhanced by 80 full color illustrations and tables, and written by US based experts in cardiovascular pharmacology, Cardiac Drugs is an invaluable resource for cardiologists and pharmacologists. Key Points Latest edition of comprehensive guide to cardiovascular pharmacology Incorporates JNC 8 guidelines on hypertension 80 full color illustrations and tables Written by US based experts in the field of cardiovascular pharmacology Previous edition (9789350258798) published 2012

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    Cardiac Drugs in Pregnancy

    300 550 

    Cardiac Drugs in Pregnancy

    de Karen Sliwa (Editor), John Anthony (Editor)

    The spectrum of cardiovascular disease affecting women in pregnancy and postpartum is changing and differs between countries. In the western world, the risk of cardiovascular disease in pregnancy has increased due to the increasing age at the first pregnancy and the worldwide obesity epidemic leading also to early diabetes and hypertension. In addition the treatment of congenital heart disease has improved leading to an increased number of women with residual heart disease reaching childbearing age. In the western world maternal heart disease is now the major cause of maternal death during pregnancy. In the developing world rheumatic heart disease and the cardiomyopathies dominate. Those women often need anticoagulation as they might have had a valve replacement or formed a thrombus in the left heart. Drugs during pregnancy and the breastfeeding period is a complex subject and there is a profound shortage of evidence based recommendations. As drug treatment in pregnancy concern the mother and the fetus optimum treatment of both must be targeted. This book aims at discussing the most important indications of drug usage in pregnancy and postpartum with the aim of weighing the potential risk of a drug and the possible benefit against each other.?

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    Cardiac Electrophysiology A Visual Guide for Nurses Techs and Fellows 2nd Edition

    de Paul D Purves (Author), George J Klein (Author)

    A practical, hands-on pictorial guide that illustrates the essential concepts of clinical cardiac electrophysiology for allied health personnel, fellows, and those new to the EP lab.

    More than 85 high-quality tracings, diagrams, fluoroscopic images, and electroanatomic maps, accompanied by detailed discussions of each image, offer a fundamental understanding of cardiac electrophysiology equipment, principles, and procedures:

    Catheter placement, hardware connections, and intracardiac signals

    Normal electrogram sequences associated with sinus rhythm

    Methodologies used to uncover the mechanisms of common clinical tachycardias

    Authored by a team of experts, Cardiac Electrophysiology: A Visual Guide for Nurses, Techs, and Fellows, Second Edition is an invaluable resource for a complex technology, providing superb guidance in acclimating new trainees and personnel to the EP laboratory and empowering them with the knowledge and skills needed to practice clinical electrophysiology.New to the Second Edition:

    A new unit?Cardiac Electrical Axis

    16 video clips with a focus on electrogram sequences

    An illustrated glossary and abbreviations list

    A free eBook included

    Full color interior in landscape format.

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    Cardiac Electrophysiology Board Review and Self Assessment

    de Milind G. Parikh (Author)

    This book offers a comprehensive review of clinical cardiac electrophysiology in a question and answer format. Chapters contain over 200 questions divided into 9 chapters, each organized by cardiac electrophysiology topic. Each question is followed by the correct answer with a detailed explanation along with references for further reading. Important concepts are highlighted and supported by over 200 illustrations and high resolution images. The book addresses a broad range of topics that are important when studying for the initial certification or recertification of the clinical cardiac electrophysiology board examination. It is also highly relevant for daily clinical practice in cardiology and cardiac electrophysiology.

    Topics covered in the book include:

    Review of basic and clinical cardiac electrophysiology principles associated with cardiac arrhythmias The evaluation and management of patients with cardiac rhythm disorders Review of pharmacologic and nonpharmacologic therapies for the treatment of arrhythmias Clinical indications, fundamental principles and electrical characteristics of implantable cardiac electronic devices such as pacemakers and defibrillators Clinical, electrocardiographic, and electrophysiologic characteristics of specific cardiac arrhythmia syndromes Cardiac Electrophysiology Board Review is a must-have resource for cardiology and cardiac electrophysiology trainees as well as attending physicians preparing for the certification or recertification examination. It may also be a useful guide for cardiologists, cardiac electrophysiologists and all clinicians who wish to further their understanding of heart rhythm disorders.

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    Cardiac Electrophysiology Methods and Models

    de Daniel C. Sigg (Editor), Paul A. Iaizzo (Editor), Yong-Fu Xiao (Editor), Bin He (Editor)

    Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

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    Cardiac Electrophysiology Without Fluoroscopy

    by Riccardo Proietti (Editor), Yan Wang (Editor), Yan Yao (Editor), Guo Qiang Zhong (Editor), Shu Lin Wu (Editor), Félix Ayala-Paredes (Editor)

    This book reflects how the concern regarding the effects of radiation exposure in patients and health personnel involved in cardiac electrophysiology (EP) has inspired new developments in cardiac electrophysiology procedures without the use of fluoroscopy. This innovative method has become a subspecialty within electrophysioloy with several EP laboratories around the world adopting an exclusive non-fluoroscopy approach. It features guidance on how to use three dimensional (3D) navigation systems, ablation energy sources and zero-fluorospic implantation of cardiac electronic devices. The potential complications and associated preventative methods with utilising RFCA are also described.

    Cardiac Electrophysiology Without Fluoroscopy offers a thorough description of the technique correlated to the performance of EP procedure without the use of radiation, and provides a valuable resource for those seeking a practically applicable guide on how to perform cardiac EP without fluoroscopy, including practising and trainee electrophysiologists, cardiac imagers, general cardiologists and emergency medicine physicians.

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    Cardiac Electrophysiology: Clinical Case Review 2nd ed

    de Andrea Natale (Editor), Paul J. Wang (Editor), Amin Al-Ahmad (Editor), N. A. Mark Estes (Editor)

    While there are many outstanding resources providing in-depth review of electrophysiology topics, this extensively updated book is one of the few case-based books that comprehensively cover clinical electrophysiology, devices and ablation. Case review offers a simple, yet effective way in teaching important concepts, offering insight into both the basic pathophysiology of a problem as well as the clinical reasoning that leads to a solution. As the field of cardiac electrophysiology evolves, the challenge remains to educate new generations of cardiac electrophysiologists with the basics as well as the latest advances in the field. Cardiac Electrophysiology: Clinical Case Review collates the most comprehensive case-based reviews of electrophysiology designed to appeal to all students of the field whether they are fellows, allied professionals or practicing electrophysiologists. The Editors have recruited some of the true experts in the field to contribute cases that they have encountered and summarizing the important learning objectives in a succinct way. Covering clinical electrophysiology, device troubleshooting and analysis as well as intracardiac electrogram analysis and ablation, readers will find the cases useful as a review of electrophysiology or in their day to day interactions with patients.

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    Cardiac Electrophysiology: From Cell to Bedside 7th Edition

    by Douglas P. Zipes MD (Author), Jose Jalife MD PhD (Author), William Gregory Stevenson MD (Author)

    Rapid advancements in cardiac electrophysiology require today's health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside . The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside , by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field.

    An attractive full-color design features color photos, tables, flow charts, ECGs, and more.

    All chapters have been significantly revised and updated by global leaders in the field, including 19 new chapters covering both basic and clinical topics. New topics include advances in basic science as well as recent clinical technology, such as leadless pacemakers; catheter ablation as a new class I recommendation for atrial fibrillation after failed medical therapy; current cardiac drugs and techniques; and a new video library covering topics that range from basic mapping (for the researcher) to clinical use (implantations). Each chapter is packed with the latest information necessary for optimal basic research as well as patient care , and additional figures, tables, and videos are readily available online. New editor William G. Stevenson, highly regarded in the EP community, brings a fresh perspective to this award-winning text. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.

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    Cardiac Emergencies in Children: A Practical Approach to Diagnosis and Management 1st ed

    de Ashok P. Sarnaik (Editor), Robert D. Ross (Editor), Steven E. Lipshultz (Editor), Henry L. Walters III (Editor)

    This book is primarily for pediatric and adult emergency room physicians, primary care providers, hospitalists, and nurses. It will also be useful for critical care specialists, cardiologists and trainees at all levels. Cardiac Emergencies in Children describes the pathophysiology of a diverse group of congenital and acquired heart conditions and presents a therapeutic rationale for treating children presenting with these conditions under life-threatening conditions. The book discusses the effects of surgery on hemodynamics and how to manage these effects. Also described are the daily challenges faced by physicians, including identifying a child with heart disease, interpreting chest radiographs, ECGs, and laboratory findings, and beginning appropriate therapies.

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    Cardiac Energy Metabolism in Health and Disease

    de Gary D. Lopaschuk (Editor), Naranjan S. Dhalla (Editor)

    The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease.

    Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

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    Cardiac Extracellular Matrix Fundamental Science to Clinical Applications

    by Eric G. Schmuck (Editor), Peiman Hematti (Editor), Amish N. Raval (Editor)

    This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.

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    Cardiac Fibrosis and Heart Failure: Cause or Effect?

    by Ian M.C. Dixon (Editor), Jeffrey T. Wigle (Editor)

    The unique biology of cardiac fibroblasts and related cells, such as cardiac myofibroblasts and valvular interstitial cells, distinguish them from other fibroblastic cells, a concept that is only beginning to be widely appreciated. Further, the natural signals that stimulate and inhibit cardiac fibrosis within these cells are not well understood. This volume compiles articles that address the molecular mechanisms that control the synthesis and secretion of the cardiac ECM. The book showcases chapters that highlight discussion of role of Transforming Growth Factor ß (TGFß), an important fibrogenic cytokine and its downstream effectors SMAD in many cardiac diseases. Further, the contributions highlight information to discuss endogenous inhibitors of cardiac fibrosis, as well as advances in tissue engineering specific to matrix in the heart. Finally, discussions of unifying mechanisms of matrix remodeling in valves and myocardium are presented.

    The mechanisms involved in the stimulation of cardiac fibrosis are not fully understood. In most cases the marginal attenuation of cardiac fibrosis as a result of a given therapy is a beneficial side-effect linked to other primary effects on other cells, especially cardiomyocytes. Very few drugs or agents are known to affect the function and dysfunction of cardiac fibroblasts and myofibroblasts alone. The book helps to translate the information gathered within to allow us to alter the course of fibrogenic events that are typical of cardiac fibrosis, and thereby reduce their burden on the patient and on society itself.

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    Cardiac Gene Expression Methods and Protocols

    by Jun Zhang (Editor), Gregg Rokosh (Editor)

    Cardiac Gene Expression: Methods and Protocols presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function.

    Section I, Cardiac Gene Expression Profiling: The Global Perspective, discusses several different approaches to examining, identifying, and analyzing changes in transcriptome gene expression. Section II, Cardiac Gene Regulation: Gene-Specific mRNA Measurement in the Myocardium, outlines more sensitive and gene-targeted expression methods. Section III, Cardiac Gene Regulation: Promoter Characterization in the Myocardium, provides protocols for the study of underlying gene regulation mechanisms by focusing on the interaction of transcription factors with their cognate cis binding elements. Section IV, In Silico Assessment of Regulatory cis-Elements and Gene Regulation, and Section V, Cardiac Single Network Polymorphisms, emphasize new analytical approaches for deciphering the functional elements buried in the 3 billion nucleotides of the human genome and other model genomes. The concluding section, Gene Overexpression and Targeting in the Myocardium, highlights methods that facilitate overexpression or cardiac-specific targeted gene deletion.

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    Cardiac Gene Therapy Methods and Protocols 2nd Edition

    de Kiyotake Ishikawa (Editor)

    This second edition volume expands on the previous edition with updated techniques and discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

    Cutting-edge and comprehensive, Cardiac Gene Therapy: Methods and Protocols, Second Edition is a valuable tool for researchers in cardiology who are conducting gene therapy research. This book will lead to further advancements and successful clinical translations in the field. Chapter “Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes Using miRcombo” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

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