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Biomarkers for Alzheimer’s Disease Drug Development (Methods in Molecular Biology Book 2785) 2nd Edition
550 ₨ – 1,250 ₨
This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies helping to accelerate Alzheimer’s disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer’s disease field are performed. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to greater success in the lab or clinic. Authoritative and practical, Biomarkers for Alzheimer’s Disease Drug Development, Second Edition seeks to inspire and inform future efforts to develop effective treatments for this devastating disease.
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Biomedical Translational Research: Drug Design and Discovery
950 ₨ – 2,150 ₨
This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.
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Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery
300 ₨ – 650 ₨
This book illustrates the influence of biomimetics in the field of tissue engineering and drug delivery. These two distinct fields of regenerative medicine have greatly benefited from the concept of biomimetics, which focuses on using or imitating nature to develop materials for improving human lives. The book begins by highlighting the relevance and recent advances in biomimetic biomaterials. An updated and innovative content has been presented in terms of biomimetic systems that are being utilized in controlled delivery and stem cell therapy. Further, the book reviews the role of these materials in enhanced capacity for drug loading, cellular uptake, and controlled release within the target cells. The book includes advanced techniques for characterizing biomimetic biomaterials and highlights their pivotal role in providing three-dimensional templates and synthetic extracellular matrices.
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CADD and Informatics in Drug Discovery (Interdisciplinary Biotechnological Advances)
600 ₨ – 1,350 ₨
This book updates knowledge on recent advances in computational, biophysical and bioinformatics tools/techniques and their practical applications in modern drug design and discovery paradigm. It also encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas; presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, R&D personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, de novo drug design, pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and systems biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to various stakeholders working in the pharmaceutical and biotechnology industries (R&D), the academic as well as research sectors.
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Cancer Drug Resistance: Methods and Protocols (Methods in Molecular Biology Book 2535)
450 ₨ – 900 ₨
This volume discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Cancer Drug Resistance: Methods and Protocols is a valuable resource for all scientists and researchers who are looking to learn more about the latest developments in understanding and overcoming anticancer drug resistance.
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Cancer Drug Safety and Public Health Policy: A Changing Landscape (Cancer Treatment and Research Book 184)
300 ₨ – 650 ₨
This book offers a wide-ranging description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. The book opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
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Carbon-Based Nanocarriers for Drug Delivery 1st Edition
550 ₨ – 1,250 ₨
Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs). It covers the applicability and suitability of CBNs as nanocarriers for efficient drug delivery application via elucidating the recent advancements in CBNs, their functionalized and innovative derivatives, and the relevant case studies. The book explores the necessity, efficacy, toxicological aspects, and challenges for the application of CBN in targeted DDSs. Some of the features of this book are provided as follows:
Provides elaborative description on significance and adaptability of carbon-based nanomaterial in targeted drug delivery for wide ranges of therapeutics
Delivers a full-spectrum discussion on drug delivery through carbon-based nanocarriers
Explores each carbon-based nanocarrier fundamentally for its drug and gene-delivery-related applications
Describes critical discussion on various toxicological effects over the utilization of these nanocarriers
Embraces existing as well as novel technologies/methodologies related to the synthesis and functionalization of CBNs, including graphene, graphene oxide, carbon quantum dots, carbon nanotube, fullerene, and smart carbon-based nanocarriers
This book is aimed at researchers and graduate students in materials and pharmaceutical engineering, including drug delivery systems.
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Carceral Recovery: Prisons, Drug Markets, and the New Pharmaceutical Self
400 ₨ – 850 ₨
The book explores the interrelation between carceral conditions and substance use by considering the intersections between drug markets, sidewalks, households, and prisons in Baltimore. Sanaullah Khan argues that while housing, medicalization, and incarceration fundamentally create the conditions for substance use, individuals are increasingly experiencing the paradoxes of care and punishment by being propelled into a new regime of recovery which creates new pharmaceuticalized identities. By shedding light on how addiction and the impetus for healing moves through families and institutions of the state, Khan provides an account of the different competing forces that shape substance use, recovery, and relapse. Through a combination of archival research and ethnography, the book makes a case for disentangling punishment from recovery.
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CAT B AID HANDBOOK OF PHARMACY TECHNICIAN EXAMINATION 2023
Original price was: 1,995 ₨.Current price is: 1,800 ₨.
CAT B AID HANDBOOK OF PHARMACY TECHNICIAN EXAMINATION 2023
Author: ATIQ UR REHMAN
Cat–B Aid: Handbook of Pharmacy Technician Examination is a compelling read for Pharmacy students who are preparing for the Category-B examination that leads to Registration in Register-B of the Pakistan Pharmacy Council. The book encloses all the six subjects that are tested by the Council each year. These subjects include Anatomy, Physiology, Biochemistry, Microbiology, Pharmacognosy, and Pharmaceutics. The author has tried his best to write each section in the simplest of words. Each topic is supported by captivating colored text, diagrams, tables, schemas, and pictures to aid in learning. The back end of the book contains over 800 multiple-choice questions from previous exams to provide easy-access test material for students.
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Cell Biology and Translational Medicine, Volume 16: Stem Cells in Tissue Regeneration, Therapy and Drug Discovery (Advances in Experimental Medicine and Biology Book 1387)
350 ₨ – 750 ₨
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions.This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 16th volume of a continuing series.
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Characterization of Nanoparticles Intended for Drug Delivery (Methods in Molecular Biology Book 2789) 3rd Edition
550 ₨ – 1,150 ₨
This third edition volume expands on the previous editions with new and updated discussions on the latest developments in endotoxin contamination, complex physicochemical properties, in vitro immunotoxicity traits, and in vitro drug release properties. Eight chapters in this book are dedicated to physicochemical characterization techniques and cover newer methods such as asymmetric-flow field-flow fractionation, single particle inductively coupled plasma mass spectrometry, and resistive pulse sensing. The next eighteen chapters explore the immunotoxicity of nanomaterials, including microbial contaminants such as endotoxin and beta-glucans, anti-PEG antibodies, autoimmunity, and immunosuppressive properties. The last two chapters talk about new pharmacology protocols, including a new technique to assess drug release and a tissue distribution assay using PEG immunohistochemistry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step instructions to reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Characterization of Nanoparticles Intended for Drug Delivery, Third Edition is a valuable resource that will help both expert and novice researchers further enhance their understanding of this important and developing field.
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Chemical Biology: and Drug Discovery
400 ₨ – 800 ₨
The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book). It gives the reader, through the specific selection of chemical biological techniques and concepts, the necessary tools to be able to develop new ways of thinking and thus new therapeutic options in the complex field of chemical biology and drug development. The stated aim of this book is to provide concrete solutions and inspiration to students, (post)graduate students, and experienced scientists at universities as well as in industry in their problems.After an introduction to the problems addressed by chemical biology in drug discovery, the three levels of molecular biology dogma: DNA, RNA and proteins and their role as drug targets serve as the common thread of this book.This book is a translation of the original German 1^st edition Chemische Biologie by Marco F. Schmidt, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2020. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.
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Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols (Methods in Molecular Biology Book 2737) 2nd Edition
750 ₨ – 1,700 ₨
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.
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Combination Drug Delivery Approach as an Effective Therapy for Various Diseases
700 ₨ – 1,600 ₨
Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches. It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations.- Provides an accounting of vital aspects on various combination drug delivery approaches, presenting next generation diagnostics and therapeutics - Discusses the perspectives of current technologies in highly organized tables, illustrative figures and flow charts - Defines major gaps in knowledge that can lead to significant scientific discoveries
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Community Pharmacy: Symptoms, Diagnosis and Treatment 5th Edition
800 ₨ – 1,600 ₨
Community Pharmacy: Symptoms, Diagnosis and Treatment 5th Edition
by Paul Rutter FFRPS MRPharmS PhD (Author)
Completely revised and updated throughout, this new edition of the best-selling title in community pharmacy continues to provide an essential reference for all non-medical prescribers but especially for undergraduate and pre-registration pharmacy trainees.
Features:
Extended information on conditions to eliminate New products covered Clearly structured by basic anatomy, history-taking and body system Fully illustrated throughout Boxes throughout: trigger points indicative of referral; hints and tips Tables throughout: differential diagnosis (key questions for each condition); evidence-based OTC medication; practical prescribing; product selection Self-assessment questions at the end of each chapter, with answer explanations Expanded case studies at the end of each chapter An enhanced ebook, with BONUS materials including:
? more self-assessment questions
? additional written case studies
? videos on physical examination
? a chapter covering evidence-based medicine
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Computational Drug Discovery and Design (Methods in Molecular Biology Book 2714) 2nd Edition
600 ₨ – 1,300 ₨
This second edition provides new and updated methods and techniques for identification of drug target, binding sites prediction, high- throughput virtual screening, lead discovery and optimization, conformational sampling, prediction of pharmacokinetic properties using computer-based methodologies. Chapters also focus on the application of the latest artificial intelligence technologies for computer aided drug discovery. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.Authoritative and cutting-edge, Computational Drug Discovery and Design, Second Edition aims to effectively utilize computational methodologies in discovery and design of novel drugs.
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Computational Drug Discovery: Methods and Applications 1st Edition
1,150 ₨ – 2,650 ₨
Computational Drug DiscoveryA comprehensive resource that explains a wide array of computational technologies and methods driving innovation in drug discoveryComputational Drug Discovery: Methods and Applications (2 volume set) covers a wide range of cutting-edge computational technologies and computational chemistry methods that are transforming drug discovery. The book delves into recent advances, particularly focusing on artificial intelligence (AI) and its application for protein structure prediction, AI-enabled virtual screening, and generative modeling for compound design. Additionally, it covers key technological advancements in computing such as quantum and cloud computing that are driving innovations in drug discovery.Furthermore, dedicated chapters that addresses the recent trends in the field of computer aided drug design, including ultra-large-scale virtual screening for hit identification, computational strategies for designing new therapeutic modalities like PROTACs and covalent inhibitors that target residues beyond cysteine are also presented.To offer the most up-to-date information on computational methods utilized in Computational Drug Discovery, it covers chapters highlighting the use of molecular dynamics and other related methods, application of QM and QM/MM methods in computational drug design, and techniques for navigating and visualizing the chemical space, as well as leveraging big data to drive drug discovery efforts.The book is thoughtfully organized into eight thematic sections, each focusing on a specific computational method or technology applied to drug discovery. Authored by renowned experts from academia, pharmaceutical industry, and major drug discovery software providers, it offers an overview of the latest advances in computational drug discovery.Key topics covered in the book include:
Application of molecular dynamics simulations and related approaches in drug discovery
The application of QM, hybrid approaches such as QM/MM, and fragment molecular orbital framework for understanding protein-ligand interactions
Adoption of artificial intelligence in pre-clinical drug discovery, encompassing protein structure prediction, generative modeling for de novo design, and virtual screening.
Techniques for navigating and visualizing the chemical space, along with harnessing big data to drive drug discovery efforts.
Methods for performing ultra-large-scale virtual screening for hit identification.
Computational strategies for designing new therapeutic models, including PROTACs and molecular glues.
In silico ADMET approaches for predicting a variety of pharmacokinetic and physicochemical endpoints.
The role of computing technologies like quantum computing and cloud computing in accelerating drug discovery
This book will provide readers an overview of the latest advancements in Computational Drug Discovery and serve as a valuable resource for professionals engaged in drug discovery.
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Computational Drug Discovery: Molecular Simulation for Medicinal Chemistry
700 ₨ – 1,600 ₨
Computational methods and understanding computational models are important in modern drug discovery. The book focuses on computational approaches that can improve the development of in silico methodologies. It includes lead hit methods, docking algorithms, computational chiral compounds, structure-based drug design, GROMACS and NAMD, structural genomics, toxicity prediction, enzyme inhibitors and peptidomimetic therapeutics
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Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches (Drug Discovery Update)
550 ₨ – 1,200 ₨
Computer-Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches outlines the basic theoretical principles, methodologies and applications of different fundamental and advanced CADD approaches and techniques. Including information on current protocols as well as recent developments in the computational methods, tools and techniques used for rational drug design, the book explains the fundamental aspects of CADD, combining this with a practical understanding of the various in silico approaches used in modern drug discovery processes to assess the field in a comprehensive and systematic manner. Providing up-to-date, information and guidance for scientists, researchers, students and teachers, the book helps readers address specific academic and research related problems using illustrative explanations, examples and case studies, which are systematically reviewed.- Highlights in silico approaches to drug design and discovery using computational tools and techniques - Details ligand-based and structure-based drug design in a comprehensive and systematic approach - Summarizes recent developments in computational drug design strategy as novel approaches of rational drug designing
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Computer Aided Pharmaceutics and Drug Delivery: An Application Guide for Students and Researchers of Pharmaceutical Sciences
1,200 ₨ – 2,750 ₨
This book examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics.This book provides abundant applications of computers in formulation designing and characterization are provided as examples, case studies and illustrations. Short reviews of software, databases and expert systems have also been added to culminate the interest of readers for novel applications in formulation development and drug delivery.Computer-aided pharmaceutics and drug delivery is an authoritative reference source for all the latest scholarly update on emerging developments in computed assisted techniques for drug designing and development. The book is ideally designed for pharmacists, medical practitioners, students and researchers. Buy online Medical books at Gangaram Jinnah Medical Books Shop for home delivery and Cash on delivery to all over Pakistan. All kind of medical books are available.

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