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    Human iPSC-derived Disease Models for Drug Discovery (Handbook of Experimental Pharmacology 281)By Markus H. Kuehn (Editor), Wei Zhu (Editor)Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has beenlost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.
     
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    Human Microanatomy is a comprehensive histology text that analyzes human structure and function from the subcellular to organ level of organization. In addition to emphasizing medically relevant information, each chapter considers developmental and evolutionary aspects of microanatomy while also using celebrity medical histories to help provide real-world context for accompanying descriptions of normal histology. The book is richly illustrated with over 1400 full-color micrographs and drawings assembled into cohesive groupings with detailed captions to help elucidate key histological concepts. Text illustrations are further supplemented by hundreds of other light and electron micrographs available in a free digital atlas covering a broad spectrum of microanatomy. Each text chapter also includes a preview, pictorial summary, and self-study quiz to highlight and review essential elements of histology. By incorporating features like medical histories, biological correlates, and various study aids, Human Microanatomy provides an appealing and informative treatment of histology for readers who are interested in the structural bases of cell, tissue, and organ functioning.KEY FEATURES:
    • Uses celebrity medical histories to help provide context for descriptions of normal histology
    • Supplements medically relevant information with developmental and evolutionary correlates of microanatomy
    • Contains 1400+ full-color micrographs and drawings that illustrate a wide range of histological features
    • Offers free access to an ancillary online atlas with hundreds of additional light and electron micrographs
    • Includes helpful study aids such as chapter previews, pictorial summaries, and self-study quizzes
    • Presents a novel and comprehensive account of the structure and function of human cells, tissues, and organs
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    Human Microbiome in Health and Disease, Volume 191, Part A presents updated knowledge on human microbiome as covered by renowned science faculty across the globe. Chapters in this volume include an introduction to human microbiome, Structure, functions and diversity of healthy human microbiome, Role of human microbiome in cancer, Gut microbiota and gastrointestinal cancer, Dysbiosis of human microbiome and metabolic diseases, Gut microbiome and type 2 diabetes, Gut microbiome and non-alcoholic fatty liver disease, Hepatic drug metabolism and intestinal microbiota, Emerging tools for understanding the human microbiome, and Microbiome therapeutics: Opportunity and challenges, and more.These chapters cover the composition, diversity, dynamics and functions of human microbiome in health and disease. This book will form an excellent and informative text on keystone, autochthonous, and exogenous microbiota important for human health in a simple to understand and easy to read format.
    • Covers the structure, functions and diversity of human microbiome in health and disease
    • Includes discussions on drug metabolisms and microbiome based therapeutics
    • Presents emerging tools for understanding the human microbiome
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    Human Movement How the Body Walks Runs Jumps and Kicks

    Price range: 250₨ through 500₨

    Human Movement How the Body Walks Runs Jumps and Kicks

    by Carla Mooney (Author), Samuel Carbaugh (Illustrator)

    Why do we walk on two legs? How do our muscles know how to work together when we dance? How does our brain work with our hands to sink a basketball? In Human Movement: How the Body Walks, Runs, Jumps, and Kicks, readers ages 12 to 15 learn the basic anatomy and physiology of the human body and discover how bones, muscles, tendons, organs, and nerves work together to make movement possible. Human Movement takes a look at all of the components of the human body and examines how they allow you to move and interact with the world around you. Readers also learn what they can do to keep their bodies healthy and fit and moving well.

    Combining hands-on activities, such as building a hand model with working muscles and tendons, with biology, chemistry, biomechanics, and nutrition, Human Movement offers entertaining graphic novel illustrations and relevant sidebars. Links to online primary sources and other important websites deepen readers’ experiences and strengthen practical connections to the material.

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    Human Naïve Pluripotent Stem Cells (Methods in Molecular Biology Book 2416)

    Price range: 500₨ through 1,100₨
    This volume provides readers with a comprehensive collection of methods to guide them on how to generate, characterize, and use naïve human pluripotent stem cells (hPSCs). The chapters in this book cover topics such as three predominant routes to generate naïve hPSC lines; methods to differentiate naïve hPSCs into specialized cell types; and techniques to characterize naïve hPSCs using key molecular landmarks that benchmark and quality control the cell lines. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Human Naïve Pluripotent Stem Cells: Methods and Protocols is a valuable resource for novice and expert researchers who are looking to learn more or expand their research in this developing field.
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    Human Osteology for Dental Students 1st Edition

    Price range: 250₨ through 450₨

    Human Osteology for Dental Students 1st Edition

    by Inderbir Singh (Author)

    Human Osteology for Dental Students is a concise guide to osteology of the human skull. Beginning with an introduction, the book discusses the anatomy of the skull, individual bones, muscles in the head and neck, and the vertebral column. Written in easy to understand language and with the help of over 100 detailed illustrations, this text guides dental students step by step through the anatomy of the skull.

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    HUMAN PHYSIOLOGY

    Original price was: 645₨.Current price is: 600₨.

    HUMAN PHYSIOLOGY

    Author: M. YUSUF ABRO

    Key Benefits: HUMAN PHYSIOLOGY: This is a study guide for the students to help them revise the subject quickly, especially during examinations. Students can extract key information about the subject very quickly, without the need to explore through textbooks. The book elaborates on the core areas, i.e., the fundamental concepts and physiological mechanisms. Each chapter concludes with some exam questions and MCQs that allow self-assessment of the desired learning outcome. Flow charts that explain physiological mechanisms A special chapter on General Principles of Physiology Essay questions and multiple-choice questions (MCQs) after each chapter.

    Unlock the Secrets of the Human Body with “Human Physiology: A Study Guide for Medical Students.” Dive into Comprehensive Understanding With the help of our well-thought-out study guide, go on an exciting voyage through the complex wonders of the human body. With thorough explanations and visual aids, learn about the intricate workings of human physiology. This section serves as your starting point for a thorough understanding of the systems, functions, and fascinating interactions within the body that keep life possible.

    Key Concepts Made Simple Handle the complexities of medical research with ease as we distill difficult physiological ideas into manageable knowledge chunks. Every chapter serves as a road map, taking you step- by-step through the most important ideas in everything from cellular biology to the cardiovascular system. Improve your education and quickly understand the fundamentals so that you can succeed in your medical coursework.

    Practical Application in Medicine Our study guide fills in the knowledge gaps between theory and practice by going beyond what is covered in textbooks. Discover the practical applications of human physiology in the field of medicine. Find out how having a solid understanding of physiological concepts can enhance clinical judgment and patient care. This section acts as a roadmap to assist you in connecting your academic understanding with the practical demands of the medical industry.

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    HUMAN PHYSIOLOGY MCQS

    Original price was: 645₨.Current price is: 600₨.

    HUMAN PHYSIOLOGY MCQS

    Author: M. YUSUF ABRO

    Key Benefits: HUMAN PHYSIOLOGY MCQS: This book serves as a revision guide to assist students in reviewing their understanding of physiology for exam preparation. It specifically aims to help students pinpoint areas requiring improvement in their knowledge and comprehension. This book is equally beneficial for undergraduate as well as postgraduate students. It will also be of great value in assessing and improving notable multiple-choice examinations like the USMLE, SAT, PLAB, GRE, and others.

    Unveiling the Marvels of Human Physiology: A Comprehensive MCQ Collection Unlocking the Body’s Mysteries With the help of our focused human physiology MCQ revision guide, take control of your exam preparation. This book is meticulously crafted to empower students by identifying and fortifying areas where improvement is needed. Engage in strategic revision sessions that go beyond passive reading, ensuring a thorough grasp of physiological concepts. Make the most of your study time and increase your self-assurance before tests.

    Master Your Medical Knowledge Boost your comprehension of human physiology with a carefully chosen series of multiple-choice questions (MCQs) that will test and broaden your medical knowledge. Whether you’re a seasoned healthcare professional or an aspiring student, these questions cover a spectrum of topics, including anatomy, biochemistry, and pathology. Take a deep dive into the science of the human body to strengthen your understanding of key ideas. With the help of this extensive MCQ resource, you can strengthen the basis for both clinical proficiency and academic success.

    Revolutionize Your Learning Experience Transform your study sessions into dynamic and effective learning experiences. Our MCQ collection isn’t just a set of questions; it’s a gateway to interactive and stimulating education. Immerse yourself in a user-friendly interface that adapts to your pace, providing instant feedback and detailed explanations. This resource is essential for a productive and interesting learning experience, regardless of whether you are studying for an exam or just discovering the mysteries of human physiology.

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    The living and the dead cohabited Paris until the late eighteenth century, when, in the name of public health, measures were taken to drive the latter from the city. Cemeteries were removed from urban space, and corpses started to be viewed as terrifyingly noxious substances.The dead had fallen victim to a sustained reflection on the notions of life and death that emerged from the two new medical fields of biology and hygiene. In large part, the Paris of the nineteenth century―the Paris of modernity―arose, both theoretically and physically, out of this concern over the relations between the animate and the inanimate.As the dead became a source of pervasive and intense anxiousness, they also became an object of fascination that at once exceeded and guided the medical imagination attempting to control them. Human Remains examines that exuberant anxiety to discover the irrational, indeed erotic, forces motivating the medicalization of death.Working across a broad range of disciplines, including history, literature, the visual arts, philosophy, and psychoanalysis, the book seeks to understand the meaning of the dead and their role in creating one of the most important cities of the contemporary world.
     
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    Human Sectional Anatomy Pocket Atlas Of Body Sections CT and MRI images 4th Edition

    by Adrian K. Dixon (Author), David J. Bowden (Author), Harold Ellis (Author), Bari M. Logan (Author)

    First published in 1991, Human Sectional Anatomy set new standards for the quality of cadaver sections and accompanying radiological images. Now in its fourth edition, this unsurpassed quality remains and is further enhanced by the addition of new material.

    The superb full-colour cadaver sections are compared with CT and MRI images, with accompanying, labelled, line diagrams. Many of the radiological images have been replaced with new examples for this latest edition, captured using the most up-to date imaging technologies to ensure excellent visualization of the anatomy. The photographic material is enhanced by useful notes with details of important anatomical and radiological features.

    Beautifully presented in a generous format, Human Sectional Anatomy continues to be an invaluable resource for all radiologists, radiographers, surgeons and medics, in training and in practice, and an essential component of departmental and general medical library collections.

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    Human Touch in Healthcare: Textbook for Therapy, Care and Medicine

    Price range: 500₨ through 1,100₨
    This textbook presents the essential research findings on human touch and haptic perception in a concise manner for students and health professionals.Focusing on anatomical, neural and physiological as well as psychological, social and clinical aspects, the scope of this book ranges from the fetus in the womb to the older adult in need of care.The chapters can be read individually or consecutively, and cross-chapter content is indicated by chapter references. Key learning points are highlighted at the end of each section, and figures, illustrations, and references facilitate the learning process.The quality of the presented study results has been critically analyzed and only randomized controlled studies are reported, which gives the reader a critical representation of the current state of knowledge. The textbook also provides valuable suggestions for future research by noting blind spots in existing research, and by pointing to methodological challenges in the implementation of high quality studies. Hence, this textbook is not only a representation of current knowledge, but also an epistemological analysis of the research process. There has been a surge of research about the sense of touch in the past ten years, which is incorporated in this book.This textbook will be an invaluable tool for physiotherapists, occupational therapists, nurses and other health professionals in everyday professional life.
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    Human Trafficking: A Global Health Emergency: Perspectives from Nursing, Criminal Justice, and the Social SciencesEdited by Mary de Chesnay and Donna Sabella
    This book presents various forms of human trafficking, a growing trend in the exploitation of large numbers of people with concurrent public health, socio-cultural, and economic costs to countries burdened with the consequences of the COVID-19 pandemic.Edited by psychiatric-mental health nurses and an applied anthropologist, this volume covers all forms of human trafficking: sex trafficking, forced labor, forced marriage, baby trafficking, organ trafficking, child marriage, and child soldiers with a global public health and policy focus. As such, it fills a gap in human trafficking knowledge and is built on courses springing up around the United States in multiple disciplines. Medical, mental health, and social work interventions are included as well as information about programs with documented outcomes.Each chapter includes state of the art of knowledge with case studies illustrating specific focal ideas, discussion, questions and exercises in order to help readers retain and reinforce chapter material. This textbook will be useful in the disciplines of nursing, medicine, public health, social work, and policy making, as well as in disciplines in which human trafficking is a current interest, such as law, criminal justice, and education. 
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    This book aims to introduce in everyday language the profound culture and unique legacy of the ancient healing art with mesmerizing stories, allusions and anecdotes in the history of its evolution, handpicked from three perspectives, including contributions of master TCM practitioners, the nourishment of TCM by traditional Chinese culture, and the exchanges between TCM and its western counterparts. The vivid narrative of each section is complemented with elaboration of one related key TCM concept in a specific column. It is a brilliant reader for those interested in TCM and traditional Chinese culture.
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    Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials provides a practical introduction to unconditional approaches to planning randomised clinical trials, particularly aimed at drug development in the pharmaceutical industry. This book is aimed at providing guidance to practitioners in using average power, assurance and related concepts. This book brings together recent research and sets them in a consistent framework and provides a fresh insight into how such methods can be used.Features:
    • A focuson normal theory linking average power, expected power, predictive power, assurance, conditional Bayesian power and Bayesian power.
    • Extensions of the concepts to binomial, and time-to-event outcomes and non-inferiority trials
    • An investigation into the upper bound on average power, assurance and Bayesian power based on the prior probability of a positive treatment effect
    • Application of assurance to a series of trials in a development program and an introduction of the assurance of an individual trial conditional on the positive outcome of an earlier trial in the program, or to the successful outcome of an interim analysis
    • Prior distribution of power and sample size
    • Extension of the basic approach to proof-of-concept trials with dual success criteria
    • Investigation of the connection betweenconditional and predictive power at an interim analysis and power and assurance
    • Introduction of the idea of surety in sample sizing of clinical trials based on the width of the confidence intervals for the treatment effect, and an unconditional version.
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    This book provides an overview of endocrine diseases associated with alterations of salt metabolism, with a focus on clinical and pathophysiological aspects. It covers various topics in the endocrine control of salt and water homeostasis, such as neuroendocrine determinants of water balance, adrenal hormone biosynthesis, hormonal function in target renal cells, and dysfunction of hormonal target effectors in the kidney. It also features an update on the clinical management of these diseases, including new diagnostic and therapeutic tools.Written by a combination of recognized and emerging experts in the field, this book is intended as a major reference work, not only for endocrinologists and nephrologists, but also for pediatricians, neonatologists, cardiologists, and emergency medicine and intensive care specialists, who can be faced with the management of endocrine diseases responsible of salt and water imbalance.The book is part of the SpringerReference program, which provides access to ‘living editions’ that are constantly updated using a dynamic, peer-review publishing process.
     
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    Hydrogen Sulfide in Kidney Diseases: A Novel Pharmacotherapy

    Price range: 400₨ through 900₨
    Hydrogen Sulfide in Kidney Diseases: A Novel PharmacotherapyBy George J. Dugbartey and Alp SenerThis is the first book to present the beneficial effects of hydrogen sulfide in the treatment of various kidney pathologies. Hydrogen sulfide (H2S), a gas with a distinctive smell of rotten eggs, was known for over three centuries for its toxicity and death at high concentrations especially among agricultural and industrial workers. This is due to its ability to reversibly antagonize complex IV of the mitochondrial electron transport chain. However, studies over the past two decades have shown that H2S has risen above its historic notorious label and has received significant experimental attention as an endogenously produced gaseous signaling molecule that plays an important role in cellular homeostasis and influences a myriad of physiological and pathological processes at low concentrations. Its production is enzymatically regulated and has specific molecular targets. Several recent in vitro and in vivo studies have demonstrated that at low micromolar concentrations, H2S exhibits important therapeutic characteristics that target multiple molecular pathways and thereby preventing the development and progression of several pathologies.This beneficial effect of H2S suggests that it may meet the demand for alternative and/or additional therapeutic agents against various renal pathologies in which reduced levels of renal and plasma H2S were observed. Interestingly, while the distribution of H2S-producing enzymes is tissue-specific, they are abundantly expressed in the glomeruli and in the brush border and cytoplasm of epithelial cells of the renal tubules and in the peritubular capillaries. This makes the kidney a rich source of endogenous H2S production. From pre-clinical and clinical perspectives, this book is topical and timely, and seeks to lay the foundation for future clinical applications of H2S in nephrology.
     
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    HYDROGEN SULFIDECovers H2S interactions, methods of detection and delivery in biological environments, and a wide range of applicationsResearch on hydrogen sulfide (H2S) spans diverse disciplines including chemistry, biology, and physiology. In recent years, new materials and approaches have been developed to deliver H2S and related reactive sulfur species in various clinical contexts. Although many biological pathways involving H2S are complex, all are governed by fundamental chemical interactions between reactive sulfur species and other molecular entities.Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies provides the foundation required for understanding the fundamental chemical biology of H2S while highlighting the compound’s therapeutic potential and medicinal applications. This book covers key aspects of H2S chemical biology, including the fundamental chemistry of reactive sulfur species; the measurement, detection, and delivery of H2S in biological environments; and the therapeutic and medicinal uses of exogenous H2S delivery in various pharmacologically relevant systems. Throughout the text, editor Michael Pluth and chapter contributors discuss the opportunities and future of the multidisciplinary field.
    • Provides approaches for delivering H2S with relevance to biological and therapeutic applications
    • Describes complex interactions of H2S with bioinorganic complexes and reactive sulfur, nitrogen, and oxygen species
    • Summarizes advances in available tools to detect, measure, and modulate H2S levels in biological environments, such as real-time methods for H2S fluorescence imaging in live cell and animal systems
    • Helps readers understand known systems and make connections to new and undiscovered pathways and mechanisms of action
    • Includes in-depth case studies of different systems in which H2S plays an important role
    Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies is an important source of current knowledge for researchers, academics, graduate students, and industrial scientists in the fields of redox biology, hydrogen sulfide research, and medicinal chemistry of small biological molecules.
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    While there are some books that include discussions of individual causes of hypercalcemia, there are none that provide basic guidance on the approach, diagnosis and treatment of hypercalcemia, while also offering an in-depth, detailed, state-of-the-art review of the individual causes by world-renowned experts in the field. Topics discussed include pathophysiology, differing diagnostic strategies for both the pediatric and adult patient, the various forms and causes of hypercalcemia as well as current treatment regimens and algorithms. Selected chapters are enhanced with illustrative cases, thereby complementing theoretical matter with real-world applications to the practice of medicine, and tables and figures allow the reader to solidify concepts in an easily digestible format. By integrating an evidence- and guideline-based framework along with an up-to-date, research-based summary of each cause, Hypercalcemia is relevantfor expert clinicians and up-and-coming medical students alike.
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    Hyperopia and Presbyopia (Refractive Surgery Book 2) 1st Edition

    Price range: 650₨ through 1,300₨

    Hyperopia and Presbyopia (Refractive Surgery Book 2) 1st Edition

    by Kazuo Tsubota (Editor), Brian S. Boxer Wachler (Editor), Dimitri T. Azar (Editor), Douglas Koch (Editor)

    Examining established and emerging treatments for the correction of hyperopia and presbyopia, this reference offers guidance on technologies such as thermal or conductive keratoplasty, corneal implants, laser scleral relaxation, scleral expansion rings, intraocular lenses, and LASIK modifications.

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    Hypertension (Oxford Cardiology Library) 3rd edition

    Price range: 500₨ through 1,050₨
    The management of hypertension varies considerably from clinician to clinician. This pocketbook is a concise and evidence-based summary of current understanding and practice, including the most up-to-date guidance from national and international bodies and their recommendations for hypertension care.Written by an international team of experts, it covers all the key aspects of hypertension from epidemiology and aetiology to investigations, management, and complications. It also covers the management of hypertension in special patient groups such as in pregnancy and the elderly. Emphasis is laid throughout the book on lowering cardiovascular risk as a part of managing hypertension. An essential tool for everyday use in managing hypertension, this book aids clinical decision-making by collating all the relevant information and guidance in one easily accessible place.This new edition has been fully updated to include expanded content on hypertension mediated organ damage and two new chapters covering the effects of hypertension on the brain and on the eyes.

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